What antibiotics are used to treat prostatitis?

In some cases, antibiotics are included in the treatment regimen for prostatitis. The choice of a particular drug depends on several factors. Antimicrobial therapy for acute and chronic forms of the disease has some significant differences.

Oral antibiotics are an important component in the successful treatment of acute and chronic prostatitis. The success of treatment largely depends on the correct selection of the drug and the medication plan.

Indications for the appointment and effect of antibiotics on prostatitis

Antibiotics are prescribed when it is clear that prostatitis is caused by an infection. This applies not only to the acute phase of the disease, when pronounced symptoms necessitate urgent assistance. Chronic bacterial prostatitis, which occurs with a mild clinical presentation or with no symptoms, also requires antibiotic treatment.

Indications for antibiotics are not some specific symptom, but laboratory data indicating the presence of an infection.

To do this, use PCR (polymerase chain reaction method), which with high accuracy allows you to determine sexually transmitted infections, as well as to study urinary excretion and glandsprostate, allowing you to detect the presence of bacteria.

Sometimes inflammation develops in the background - in this case, the level of white blood cells in the secretory gland does not exceed the normal level. To determine if an infection is present, your doctor will prescribe an experimental antibiotic. After a week of taking this drug, the analysis is carried out again, and if the level of leukocytes is above 25 units, we are talking about a hidden course of an infectious lesion of the prostate gland. In this case, antibiotics become mandatory.

The choice of antibiotic to treat prostatitis depends on several factors. What is important is which bacteria have been identified and to which drugs they are susceptible. There is no universal cure.

The principle of action of antibiotics depends on the drug used, the form of the disease and the inflammatory agent. However, the general nature can be reduced to several stages:

  1. The drug enters the bloodstream by assimilation through the gastrointestinal tract or by intravenous administration.
  2. The penetration of active substances into the tissues of the prostate gland and destruction of the causative agent.
  3. The effect accumulates in the tissues of the gland, allowing you to constantly fight infections.

The last step is especially important, since some antibiotics are only bacteriostatic. This means they only affect cells that are dividing. At the same time, cells in an anaerobic state remain unnoticed by them. If the active substance of the drug does not accumulate in the tissues of the prostate gland, then the bacteria that have left the anaerobic state will quickly negate the entire effect of the treatment.

There are bacteria that are highly resistant to antibiotics. These are probably the most common prostatitis pathogens, such as Escherichia coli. They form hard capsules and biofilms that reduce the effects of the active drug ingredients. In this case, what is needed is drugs capable of destroying the protective coatings of these bacteria. It is also important to take the medicine to the end, even if the symptoms of the disease have disappeared.

Groups of antibacterial agents for the treatment of prostatitis

There are several classes of antibiotics that are effective (single or in combination) against the bacteria that cause prostatitis. The choice of a particular class of drugs depends on several factors: the "weakness" in the bacteria is identified, the patient's comorbidities, the severity of the prostatitis process, its form andSide effects of medications.

The main classes of antibacterial drugs for prostatitis include:

  • tetracyclines;
  • penicillin;
  • cephalosporins;
  • macrolite;
  • fluoroquinolones.

tetracycline chain

Antibiotics of this group have a bacteriostatic effect, that is, they inhibit the process of cell division, growth and development.

Don't think that bacteriostatic drugs are clearly ineffective. This effect is sufficient to clear the infection, provided that the patient is not immunocompromised.

Such drugs disrupt the connection between RNA ("commands" the growth and division of pathogens) and ribosomes (which perform this "command"), thereby blocking the production of proteins - the building blocks of the pathogen. build new cells.

man taking antibiotics to treat prostatitis

Drugs of this group are effective in the fight against the following pathogens:

  • mycoplasmas;
  • ureaplasma;
  • chlamydia;
  • enterococci;
  • intestinal bacteria;
  • klebsiella;
  • pseudomonas;
  • isolation;
  • coli.

Drugs in this class are prescribed selectively because of their wide range of side effects.

Penicillin Series

Preparations of this group also have a bacteriostatic effect, affecting dividing bacteria. However, they have a different principle of operation: they stop the production of the main component of the bacterial cell wall - peptidoglycan.

Since many bacteria have developed antibiotic resistance in this group, a subgroup of protected penicillins has been developed.

These antibiotics are effective in treating inflammation caused by the following bacteria:

  • gonococci;
  • staphylococci;
  • intestinal bacteria;
  • Proteus;
  • klebsiella;
  • isolation;
  • coli.

Drugs of this group are prescribed with caution due to the high risk of allergic reactions. For the treatment of prostatitis, drugs based on oxacillin, ampicillin and amoxicillin are prescribed.


These are powerful bactericidal drugs that not only stop cell division but also destroy them. This happens in two steps: interruption of peptidoglycan production (destruction of cell walls) and release of enzymes.

Drugs of this group are effective against:

  • gonococci;
  • intestinal bacteria;
  • Proteus bacteria;
  • Klebsiella;
  • coli.

Drugs in this class include drugs based on ceftriaxone, cefilin, cefpiron, and others.


The safest group of antibiotics, with the fewest side effects. Their principle of action is to stop the production of proteins to build cells. How effective it will be (bactericidal or bacteriostatic) depends on the choice of drug and its concentration in the body.

A man is studying the caption for an antibiotic for prostatitis

Antibiotics from this group are effective against the following bacteria:

  • gonococci;
  • chlamydia;
  • ureaplasma;
  • mycoplasmas.

Not all physicians prescribe drugs in this class for the treatment of prostatitis, because, although their effects are reasonable to assume, narrow studies have not been performed on subjects. this. Drugs in this group include drugs based on azithromycin and clarithromycin.


These are not antibiotics in their classical sense, because antibiotics are drugs of natural origin or their closest synthetic counterpart. Fluoroquinolones have no analogues in nature.

Drugs of this particular class are usually prescribed by urologists. And there are good reasons for this:

  • Firstly, they have a very broad bactericidal spectrum, not inferior to natural antibiotics with fewer side effects.
  • Second, they have a very positive antibacterial effect: they affect both the production of DNA, preventing its replication, and topoisomerase (an important part of the virus's integration into the cell). ) and RNA, and the wall of cell membranes and other processes. ensure vital activity and cell division - such a massive attack from all fronts has good results.

Fluoroquinolones are effective against:

  • intestine and Pseudomonas aeruginosa;
  • staphylococci;
  • gonococci;
  • mycoplasmas;
  • chlamydia and other bacteria.

Antibiotics of this group are used for complex treatment of Koch bacilli. Therefore, before you start taking these medicines, it is important to make sure that there is no TB-causing agent in your body. The fact is that individual absorption of fluoroquinolones helps Koch's rods develop resistance to other antibiotics, and the treatment of tuberculosis becomes much more complicated.

The most effective antibiotic for prostatitis

Even the most effective antibiotic will be useless and even harmful if the reason for choosing this drug is advertising, the opinion of incompetent people who have been helped by this remedy, or the factthat the drug worked last time. There is no single drug that is active against all bacteria and viruses, but each class of antibiotics has its best representatives.

General principles and features of antibiotic therapy for acute and chronic prostatitis

The treatment regimen and choice of medication depend on the form of prostatitis. There are both similarities and differences in the treatment of acute and chronic prostatitis.

For antibiotic therapy for any type of prostatitis, the following are characteristics:

  • contact a doctor and pass tests to determine the pathogen is required;
  • should continue treatment according to the program, even if it seems that full recovery has come.

At the same time, when choosing a drug to treat an infection, you need to keep a number of different factors in mind. Therefore, for the treatment of chronic prostatitis, the ability of the active substance to penetrate the cells of the prostate gland is fundamentally important. It has been shown that only a high concentration of the drug in the blood is not enough. Not all broad-spectrum drugs, even the newest generations, have such capabilities. The situation is different with acute inflammation: it increases the permeability of prostate cells to allow drugs from the bloodstream to enter.

The ability of drugs to penetrate and accumulate in tissues is of fundamental importance in chronic inflammation, but not so important in acute inflammation.

The second difference is that the acute phase should be treated as quickly as possible, depending on the severity of the condition. Therefore, people prefer to use bactericidal drugs (fluoroquinolones) over bacteriostatic drugs. In cases where the principle of action of the drug depends on the dose, the concentration of the drug in the blood and prostate gland must be sufficient to maintain the bactericidal effect - this applies to drugs from the macrolide group.

Bacteriostatic antibiotics of choice for chronic inflammation and bactericidal antibiotics for acute inflammation.

Natural antibiotics: effectiveness and methods of application

Considering that almost all antibiotics are of natural origin (or are the closest analogues), it is reasonable to assume that herbs have a similar effect with good tolerability. and with fewer side effects.

However, if the activity of the herbs is sufficient, no drug production will be required. Therefore, herbal therapy with antibacterial properties is appropriate only as an adjuvant or prophylactic treatment for chronic prostatitis.

There are several herbs that can fight bacteria:

  • yarrow (may have both bactericidal and bacteriostatic effects on E. coli and enterobacteria);
  • sage (effective against Escherichia and Pseudomonas aeruginosa);
  • eleutherococcus (against staphylococcus aureus, E. coli and enteric bacteria);
  • big tree (anti-staphylococci, intestinal bacteria, bacteriostatic effect on proteus, analgesic effect).

There are many recipes by which you can prepare an antibacterial medicine to reduce inflammation. From herbs, it is better to prepare an infusion that does not require long exposure to heat.

herbal decoction as a natural antibiotic for prostatitis

For almost any herb, the following recipe is suitable:

  1. For one part herb, take ten parts room temperature water.
  2. Heat the mixture for a quarter of an hour in a boiling water bath.
  3. Soak for 45 minutes.
  4. Pass through a filter, such as gauze.

The infusion is most effective if given immediately after preparation.

In addition, to combat prostatitis, people use witch hazel, fern and chestnut bark. From such material it is better to prepare a decoction. Each type of plant has its own recipe, but in general, the way to prepare the decoction is as follows:

  1. Wash and grind ingredients.
  2. Add water to cover all branches or bark.
  3. Boil in water bath for half an hour.
  4. Let cool for 10 minutes, then drain the broth, squeeze out the ingredients.

Broth can be made within 2 days from the time of preparation.

The effectiveness of the treatment depends on several factors: the selection of the desired natural antibiotic, the purchase of high-quality ingredients (it is better to prepare your own) and the correct preparation of the infusion or decoction.

Antibiotics for prostatitis are chosen depending on the infection causing the inflammation, the form of the disease, and the general health of the patient. Each drug has contraindications and side effects, so you should consult a urologist before taking it. The same applies to medicinal herbs that have an antibacterial effect.